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Add  A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo
Authors: Tarasenko, Nataly. | Cutts, Suzanne. | Phillips, Don R. | Berkovitch-Luria, Gili. | Bardugo-Nissim, Elinor. | Weitman, Michal. | Nudelman, Abrahim. | Rephaeli, Ada.
Date: 2014
Subject: 060199 Biochemistry and Cell Biology not elsewhere classified | 111205 Chemotherapy
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/513763
Description: Funding Information Note: This work was supported in part by grants from The Israel Cancer Research Fund
Add  The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts
Authors: Forrest, Robert A. | Swift, Lonnie P. | Evison, Benny J. | Rephaeli, Ada. | Nudelman, Abraham. | Phillips, Don R. | Cutts, Suzanne.
Date: 2013
Subject: 060199 Biochemistry and Cell Biology not elsewhere classified | 111205 Chemotherapy
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/497501
Description: First published online 2012.
Add  Disparate Impact of Butyroyloxymethyl Diethylphosphate (AN-7), a Histone Deacetylase Inhibitor, and Doxorubicin in Mice Bearing a Mammary Tumor
Authors: Tarasenko, Nataly. | Cutts, Suzanne. | Phillips, Don R. | Inbal, Aida. | Nudelman, Abrahim. | Kessler-Icekson, Gania. | Rephaeli, Ada.
Date: 2012
Subject: 060199 Biochemistry and Cell Biology not elsewhere classified | 110105 Medical Biochemistry: Nucleic Acids | 111205 Chemotherapy
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/531024
Description: Funding Information Note: The work was supported by Israel Cancer Association (Grant No 20092001).
Full Text: Full Text
Add  Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor.
Authors: Tarasenko, Nataly. | Cutts, Suzanne M. | Phillips, Don R. | Inbal, Aida. | Nudelman, Abraham. | Kessler-Icekson, Gania. | Rephaeli, Ada.
Date: 2012
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/441092
Description: DEST category:C1 - Journal Articles - Refereed article
Add  ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin-DNA adducts.
Authors: Ugarenko, Michal. | Nudelman, Abraham. | Rephaeli, Ada. | Kimura, Ken-Ichi. | Phillips, Don R. | Cutts, Suzanne M.
Date: 2010.
Subject: 0601 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/390925
Description: DEST collection year : 2011
Add  New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation.
Authors: Mansour, Oula C. | Evison, Benny J. | Sleebs, Brad E. | Watson, Keith G. | Nudelman, Abraham. | Rephaeli, Ada. | Buck, Damian P. | Collins, J. Grant. | Bilardi, Rebecca A. | Phillips, Don R. | Cutts, Suzanne M.
Date: 2010.
Subject: 0304 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/364781
Description: DEST collection year : 2011
Add  Development of Pluronic micelle-encapsulated doxorubicin and formaldehyde-releasing prodrugs for localized anticancer chemotherapy.
Authors: Ugarenko, Michael. | Chan, Chee Kai. | Nudelman, Abraham. | Rephaeli, Ada. | Cutts, Suzanne Margaret. | Phillips, Donald Ralph.
Date: 2009.
Subject: 060103 Cell Development, Proliferation and Death | 1112 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/459700
Description: DEST collection year : 2010
Add  Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species.
Authors: Levovich, Inesa. | Nudelman, Abraham. | Berkovitch, Gili. | Swift, Lonnie Peter. | Cutts, Suzanne Margaret. | Phillips, Donald Ralph. | Rephaeli, Ada.
Date: 2008.
Subject: 111500 Pharmacology and Pharmaceutical Sciences | 0601 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/410324
Description: DEST collection year : 2009
Add  The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity.
Authors: Swift, Lonnie Peter. | Cutts, Suzanne Margaret. | Nudelman, Abraham. | Levovich, Inesa. | Rephaeli, Ada. | Phillips, Donald Ralph.
Date: 2008.
Subject: 111500 Pharmacology and Pharmaceutical Sciences | 1115 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/424310
Description: First published online 2007.
Add  Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate.
Authors: Cutts, Suzanne M. | Swift, Lonnie P. | Pillay, Vinochani. | Forrest, Robert A. | Nudelman, Abraham. | Rephaeli, Ada. | Phillips, Don R.
Date: 2007.
Subject: 111200 Oncology and Carcinogenesis | 1112 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/462499
Description: DEST collection year : 2008
Add  Doxorubicin-DNA Adducts Induce a Non-Topoisomerase 11-Mediated Form of Cell Death
Authors: Swift, Lonnie. | Rephaeli, Ada. | Nudelman, Abraham. | Phillips, Donald. | Cutts, Suzanne. | School of Molecular Sciences.
Date: 2006.
Subject: 270100 Biochemistry and Cell Biology | 111200 Oncology and Carcinogenesis | 0601 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/333341
Description: DEST collection year:2007
Full Text: Full Text
Add  Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines.
Authors: Engel, D. | Nudelman, Abraham. | Levovich, I. | Gruss-Fischer, Tal. | Entin-Meer, M. | Phillips, Donald. | Cutts, Suzanne. | Rephaeli, Ada.
Date: 2006.
Subject: 270100 Biochemistry and Cell Biology | 111200 Oncology and Carcinogenesis | 1112 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/486721
Description: DEST collection year:2007
Add  The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs.
Authors: Rephaeli, Ada. | Entin-Meer, M. | Angel, Dikla. | Tarasenko, Nataly. | Gruss-Fischer, Tal. | Bruachman, Irena. | Phillips, Donald. | Cutts, Suzanne. | Haas-Kogan, Daphne. | Nudelman, Abraham.
Date: 2006.
Subject: 270100 Biochemistry and Cell Biology | 111500 Pharmacology and Pharmaceutical Sciences | 0601 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/414080
Description: DEST collection year:2007
Add  Formaldehyde-releasing prodrugs in combination with Adriamycin can overcome cellular drug resistance.
Authors: Cutts, Suzanne M. | Nudelman, Abraham. | Pillay, Vinochani. | Spencer, Damian M. S. | Levovich, Inesa. | Rephaeli, Ada. | Phillips, Don R. | School of Molecular Sciences.
Date: 2005.
Subject: 270102 Cell Metabolism | 111200 Oncology and Carcinogenesis | 1112 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/463484
Description: DEST collection year:2006
Add  In vivo and in vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer.
Authors: Rephaeli, Ada. | Blank-Porat, Diana. | Tarasenko, Nataly. | Entin-Meer, Michal. | Levovich, Inesa. | Cutts, Suzanne M. | Phillips, Don R. | Malik, Zvi. | Nudelman, Abraham.
Date: 2005.
Subject: 270100 Biochemistry and Cell Biology | 111200 Oncology and Carcinogenesis | 0601 (four-digit-FOR)
Language: en
Type: journal article
Identifier: http://hdl.handle.net/1959.9/434406
Description: DEST collection year:2006