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This is the author’s version of a work that was accepted for publication in Cellular and Molecular Life Sciences. Changes resulting from the publishing process, such as copy-editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version of this work was published by Springer, this version can be found at http://dx.doi.org/10.1007/s00018-018-2932-7 (Please note: access via this link may only be available with a subscription).
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Cellular and Molecular Life Sciences, 76(2): 245-257